As in decades past, the nation’s regulatory agencies have been slow — some say negligent — to recognize this fast-growing threat to the health and development of young Americans. Rome, a pediatrician who heads the Center for Adolescent Medicine at the Cleveland Clinic, explained that nicotine forms addictive pathways in the brain that can increase a youngster’s susceptibility to addiction throughout life. The adolescent brain is still developing, she told me, and e-cigarette use is often a gateway to vaping of marijuana, which can affect the brain centers responsible for attention, memory, learning, cognition, self-control and decision-making.

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